BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM50296560'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50296560
PNG
(CHEMBL558845 | N-(2-(6-oxo-6,7,8,9-tetrahydro-3H-p...)
Show SMILES O=C(NCCc1c[nH]c2ccc3C(=O)NCCc3c12)N1CCNCC1
Show InChI InChI=1S/C18H23N5O2/c24-17-14-1-2-15-16(13(14)4-6-20-17)12(11-22-15)3-5-21-18(25)23-9-7-19-8-10-23/h1-2,11,19,22H,3-10H2,(H,20,24)(H,21,25)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 25n/an/an/an/an/an/a



IRBM--Merck Research Laboratories Rome

Curated by ChEMBL


Assay Description
Inhibition of PARP1 in human HeLa cells by microplate scintillation counting

Bioorg Med Chem Lett 19: 4042-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.06.031
BindingDB Entry DOI: 10.7270/Q2WH2Q09
More data for this
Ligand-Target Pair