BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 1' and Ligand = 'BDBM50306205'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50306205
PNG
(2-(4-(pyridin-4-ylmethylcarbamoyl)phenyl)-2H-indaz...)
Show SMILES NC(=O)c1cccc2cn(nc12)-c1ccc(cc1)C(=O)NCc1ccncc1
Show InChI InChI=1S/C21H17N5O2/c22-20(27)18-3-1-2-16-13-26(25-19(16)18)17-6-4-15(5-7-17)21(28)24-12-14-8-10-23-11-9-14/h1-11,13H,12H2,(H2,22,27)(H,24,28)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



IRBM-Merck Research Laboratories Rome

Curated by ChEMBL


Assay Description
Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assay

Bioorg Med Chem Lett 20: 488-92 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.127
BindingDB Entry DOI: 10.7270/Q2W37WFZ
More data for this
Ligand-Target Pair