Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase 2' and Ligand = 'BDBM191218'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 2 (Homo sapiens (Human))	BDBM191218 (US9181266, 87) Show SMILES O=C(CN1CCC(CC1)C(=O)c1ccc(OC2CCOCC2)cc1)NCc1nc2CCOCc2c(=O)[nH]1 Show InChI InChI=1S/C27H34N4O6/c32-25(28-15-24-29-23-9-14-36-17-22(23)27(34)30-24)16-31-10-5-19(6-11-31)26(33)18-1-3-20(4-2-18)37-21-7-12-35-13-8-21/h1-4,19,21H,5-17H2,(H,28,32)(H,29,30,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.84E+3	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...				US Patent US9181266 (2015) BindingDB Entry DOI: 10.7270/Q20P0XTF
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