Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-1' and Ligand = 'BDBM185822'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human))	BDBM185822 (US9163003, 36 | USRE46942, Example 36) Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C1CCN(CC(=O)Nc2nnnn2C)C1=O Show InChI InChI=1S/C21H27N7O4/c1-26-21(23-24-25-26)22-18(29)13-28-12-9-17(20(28)31)27-10-7-15(8-11-27)19(30)14-3-5-16(32-2)6-4-14/h3-6,15,17H,7-13H2,1-2H3,(H,22,23,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...				US Patent USRE46942 (2018) BindingDB Entry DOI: 10.7270/Q2VX0JVH
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human))	BDBM185822 (US9163003, 36 | USRE46942, Example 36) Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C1CCN(CC(=O)Nc2nnnn2C)C1=O Show InChI InChI=1S/C21H27N7O4/c1-26-21(23-24-25-26)22-18(29)13-28-12-9-17(20(28)31)27-10-7-15(8-11-27)19(30)14-3-5-16(32-2)6-4-14/h3-6,15,17H,7-13H2,1-2H3,(H,22,23,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.08E+3	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...				US Patent US9163003 (2015) BindingDB Entry DOI: 10.7270/Q2QN65J6
					More data for this Ligand-Target Pair