Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325]' and Ligand = 'BDBM231073'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] (Homo sapiens (Human))	BDBM231073 (US9340549, 97) Show SMILES CC1(C)OC(=O)N([C@H]1c1ccccc1)[C@H]1CC[C@@H](CC1)c1c[nH]c(=O)c(c1)-c1ncccn1 |r,wU:17.22,7.8,wD:14.15,(-6.5,5.39,;-5.16,4.62,;-6.5,3.85,;-4.26,5.87,;-2.79,5.39,;-1.46,6.16,;-2.79,3.85,;-4.26,3.37,;-4.66,1.89,;-6.14,1.49,;-6.54,0,;-5.45,-1.09,;-3.97,-.69,;-3.57,.8,;-1.46,3.08,;-1.46,1.54,;-.13,.77,;1.21,1.54,;1.21,3.08,;-.13,3.85,;2.54,.77,;3.88,1.54,;5.21,.77,;5.21,-.77,;6.54,-1.54,;3.88,-1.54,;2.54,-.77,;3.88,-3.08,;2.54,-3.85,;2.54,-5.39,;3.88,-6.16,;5.21,-5.39,;5.21,-3.85,)| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	267	n/a	n/a	n/a	n/a	n/a	25
AMGEN INC. US Patent					Assay Description The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...				US Patent US9340549 (2016) BindingDB Entry DOI: 10.7270/Q2SN07VD
					More data for this Ligand-Target Pair