Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325]' and Ligand = 'BDBM231115'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-1 [1091-1325] (Homo sapiens (Human))	BDBM231115 (US9340549, 140) Show SMILES CC1(C)OC(=O)N([C@H]1c1ccccc1)C1CCN(CC1)c1cnc2ccn(-c3ncccn3)c2c1 |r| Show InChI InChI=1S/C27H28N6O2/c1-27(2)24(19-7-4-3-5-8-19)33(26(34)35-27)20-9-14-31(15-10-20)21-17-23-22(30-18-21)11-16-32(23)25-28-12-6-13-29-25/h3-8,11-13,16-18,20,24H,9-10,14-15H2,1-2H3/t24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24.3	n/a	n/a	n/a	n/a	n/a	25
AMGEN INC. US Patent					Assay Description The tankyrase 1 biochemical activity of the compounds was assayed in the following assay buffer (50 mM MOPS pH7.5, 100 mM NaCl, 2.5 mM MgCl2, 0.01% T...				US Patent US9340549 (2016) BindingDB Entry DOI: 10.7270/Q2SN07VD
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