Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM185793'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM185793 (US9163003, 1) Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C1CCN(Cc2cccc(Cl)c2[N+]#[C-])C1=O Show InChI InChI=1S/C25H26ClN3O3/c1-27-23-19(4-3-5-21(23)26)16-29-15-12-22(25(29)31)28-13-10-18(11-14-28)24(30)17-6-8-20(32-2)9-7-17/h3-9,18,22H,10-16H2,2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...				US Patent US9163003 (2015) BindingDB Entry DOI: 10.7270/Q2QN65J6
					More data for this Ligand-Target Pair