Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM185828'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM185828 (US9163003, 34 | USRE46942, Example 33) Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)[C@@H]1CCN(CC(=O)Nc2nnc3SCCn23)C1=O Show InChI InChI=1S/C23H28N6O4S/c1-33-17-4-2-15(3-5-17)20(31)16-6-9-27(10-7-16)18-8-11-28(21(18)32)14-19(30)24-22-25-26-23-29(22)12-13-34-23/h2-5,16,18H,6-14H2,1H3,(H,24,25,30)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...				US Patent US9163003 (2015) BindingDB Entry DOI: 10.7270/Q2QN65J6
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM185828 (US9163003, 34 | USRE46942, Example 33) Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)[C@@H]1CCN(CC(=O)Nc2nnc3SCCn23)C1=O Show InChI InChI=1S/C23H28N6O4S/c1-33-17-4-2-15(3-5-17)20(31)16-6-9-27(10-7-16)18-8-11-28(21(18)32)14-19(30)24-22-25-26-23-29(22)12-13-34-23/h2-5,16,18H,6-14H2,1H3,(H,24,25,30)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	374	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The human tankyrase 1 PARP catalytic domain, TNKS1P, was cloned into a pDONR221 vector using the Invitrogen Gateway Technology. This entry clone was ...				US Patent USRE46942 (2018) BindingDB Entry DOI: 10.7270/Q2VX0JVH
					More data for this Ligand-Target Pair