Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM191147'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM191147 (US9181266, 9) Show SMILES COc1ccc(cc1)C(=O)C1CCN(CC(=O)NCc2nc3CCCCc3c(=O)[nH]2)CC1 Show InChI InChI=1S/C24H30N4O4/c1-32-18-8-6-16(7-9-18)23(30)17-10-12-28(13-11-17)15-22(29)25-14-21-26-20-5-3-2-4-19(20)24(31)27-21/h6-9,17H,2-5,10-15H2,1H3,(H,25,29)(H,26,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	25
NOVARTIS AG US Patent					Assay Description The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...				US Patent US9181266 (2015) BindingDB Entry DOI: 10.7270/Q20P0XTF
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