Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM318037'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM318037 (2-[4-[(2-Chlorophenyl)methyl]piperazin-1-yl]-8-met...) Show SMILES CN1CCCc2c1nc([nH]c2=O)N1CCN(Cc2ccccc2Cl)CC1 Show InChI InChI=1S/C19H24ClN5O/c1-23-8-4-6-15-17(23)21-19(22-18(15)26)25-11-9-24(10-12-25)13-14-5-2-3-7-16(14)20/h2-3,5,7H,4,6,8-13H2,1H3,(H,21,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30.2	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description The enzymatic activity of hTNKS1 and hTNKS2 is assessed using an enzyme-linked immunosorbent assay (ELISA) which detects poly ADP ribose incorporated...				US Patent US9624218 (2017) BindingDB Entry DOI: 10.7270/Q26112CZ
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