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Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM50462628'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase tankyrase-2


(Homo sapiens (Human))		BDBM50462628
PNG
(CHEMBL4239155)
Show SMILES COc1cc(CCCOC(C)=O)cc(c1O)-c1cc(CCCOC(C)=O)cc(OC)c1O
Show InChI InChI=1S/C24H30O8/c1-15(25)31-9-5-7-17-11-19(23(27)21(13-17)29-3)20-12-18(8-6-10-32-16(2)26)14-22(30-4)24(20)28/h11-14,27-28H,5-10H2,1-4H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 6.5n/an/an/an/an/a



University of Salerno

Curated by ChEMBL


Assay Description
Binding affinity to recombinant human N-terminal His-tagged TNKS2 (Ser959 to Gly1166 residues) expressed in Escherichia coli by surface plasmon reson...

Bioorg Med Chem 26: 3953-3957 (2018)


Article DOI: 10.1016/j.bmc.2018.06.019
BindingDB Entry DOI: 10.7270/Q2KH0R05
More data for this
Ligand-Target Pair