Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Poly [ADP-ribose] polymerase tankyrase-2' and Ligand = 'BDBM50579982'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase tankyrase-2 (Homo sapiens (Human))	BDBM50579982 (CHEMBL5087403) Show SMILES Fc1cc(C(=O)N[C@H]2C[C@@H](C2)c2nnc(-c3ccccn3)n2-c2ccccc2F)c2nccnc2c1 |r,wU:7.6,wD:9.11,(15.66,-15.79,;15.35,-17.28,;13.88,-17.76,;13.57,-19.27,;12.1,-19.76,;10.95,-18.72,;11.78,-21.27,;10.3,-21.75,;9.59,-23.12,;8.22,-22.41,;8.92,-21.04,;6.76,-22.9,;5.5,-21.98,;4.26,-22.9,;4.73,-24.37,;3.83,-25.59,;4.45,-26.98,;3.56,-28.21,;2.04,-28.05,;1.42,-26.66,;2.32,-25.43,;6.28,-24.37,;7.17,-25.6,;6.55,-26.99,;7.44,-28.22,;8.96,-28.06,;9.58,-26.66,;8.68,-25.43,;9.29,-24.04,;14.72,-20.3,;14.4,-21.81,;15.54,-22.84,;17.01,-22.36,;17.33,-20.85,;16.19,-19.83,;16.5,-18.31,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TNKS2 (873 to 1162 residues) incubated for 20 hrs in presence of NAD				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01264 BindingDB Entry DOI: 10.7270/Q21R6VDH
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