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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polycomb protein EED' and Ligand = 'BDBM50235628'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polycomb protein EED


(Homo sapiens (Human))		BDBM50235628
PNG
(CHEMBL4105413)
Show SMILES CN(C)[C@H]1CN(Cc2c(C)nc3ncccn23)C[C@@H]1c1cn(C)c2ccccc12 |r|
Show InChI InChI=1S/C23H28N6/c1-16-21(29-11-7-10-24-23(29)25-16)14-28-13-19(22(15-28)26(2)3)18-12-27(4)20-9-6-5-8-17(18)20/h5-12,19,22H,13-15H2,1-4H3/t19-,22+/m1/s1
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Similars
Article
PubMed
>5.00E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

Curated by ChEMBL


Assay Description
Inhibition of OG(488) labeled probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assay

Bioorg Med Chem Lett 27: 1576-1583 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.030
BindingDB Entry DOI: 10.7270/Q22F7QQG
More data for this
Ligand-Target Pair