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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polycomb protein EED' and Ligand = 'BDBM50235634'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polycomb protein EED


(Homo sapiens (Human))		BDBM50235634
PNG
(CHEMBL4082105)
Show SMILES CCn1cc(CN2C[C@@H]([C@H](C2)c2cn(C)c3ccccc23)N(C)C)c(C)n1 |r|
Show InChI InChI=1S/C22H31N5/c1-6-27-12-17(16(2)23-27)11-26-14-20(22(15-26)24(3)4)19-13-25(5)21-10-8-7-9-18(19)21/h7-10,12-13,20,22H,6,11,14-15H2,1-5H3/t20-,22+/m1/s1
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PC cid
PC sid
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Similars
Article
PubMed
>5.00E+4n/an/an/an/an/an/an/an/a



AbbVie Inc.

Curated by ChEMBL


Assay Description
Inhibition of OG(488) labeled probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assay

Bioorg Med Chem Lett 27: 1576-1583 (2017)


Article DOI: 10.1016/j.bmcl.2017.02.030
BindingDB Entry DOI: 10.7270/Q22F7QQG
More data for this
Ligand-Target Pair