Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Polycomb protein EED' and Ligand = 'BDBM50575295'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polycomb protein EED (Homo sapiens (Human))	BDBM50575295 (CHEMBL4850017) Show SMILES Cc1nccn1-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair
Polycomb protein EED (Homo sapiens (Human))	BDBM50575295 (CHEMBL4850017) Show SMILES Cc1nccn1-c1cnc(NCc2c3CCOc3ccc2F)c2cn[nH]c(=O)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01161 BindingDB Entry DOI: 10.7270/Q2MP5737
					More data for this Ligand-Target Pair