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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polymerase acidic protein' and Ligand = 'BDBM50463502'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polymerase acidic protein


(Influenza A virus (strain A/X-31 H3N2))		BDBM50463502
PNG
(CHEMBL4247561)
Show SMILES Oc1cc2[nH]cc(C(=O)CCN3CCC(Cc4ccc(F)cc4)CC3)c2cc1O
Show InChI InChI=1S/C23H25FN2O3/c24-17-3-1-15(2-4-17)11-16-5-8-26(9-6-16)10-7-21(27)19-14-25-20-13-23(29)22(28)12-18(19)20/h1-4,12-14,16,25,28-29H,5-11H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.43E+5n/an/an/an/an/an/a



Polo Universitario SS. Annunziata

Curated by ChEMBL


Assay Description
Inhibition of recombinant Influenza A virus (A/X-31(H3N2)) N-terminal 6xHis-tagged PA-Nter (1 to 217 residues) expressed in Escherichia coli BL21-Cod...

Bioorg Med Chem 26: 4544-4550 (2018)


Article DOI: 10.1016/j.bmc.2018.07.046
BindingDB Entry DOI: 10.7270/Q2TM7DS6
More data for this
Ligand-Target Pair