BindingDB PrimarySearch

Found 10 hits Enz. Inhib. hit(s) with Target = 'Polypeptide N-acetylgalactosaminyltransferase 2' and Ligand = 'BDBM50215545'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polypeptide N-acetylgalactosaminyltransferase 2 (Homo sapiens (Human))	BDBM50215545 (CHEMBL6338) Show SMILES Oc1ccc2c3cc(O)c(O)cc3c(=O)oc2c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiao Tong University Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells using EA2 peptide as substrate by HPLC-based enzyme assa...				Bioorg Med Chem 27: 3372-3382 (2019) Article DOI: 10.1016/j.bmc.2019.06.020 BindingDB Entry DOI: 10.7270/Q2988BDQ
Shanghai Jiao Tong University Curated by ChEMBL					More data for this Ligand-Target Pair
Polypeptide N-acetylgalactosaminyltransferase 2 (Homo sapiens (Human))	BDBM50215545 (CHEMBL6338) Show SMILES Oc1ccc2c3cc(O)c(O)cc3c(=O)oc2c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	6.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiao Tong University Curated by ChEMBL					Assay Description Non-competitive inhibition of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells using UDP-GalNAc as substrate by HPLC-based enzyme a...				Bioorg Med Chem 27: 3372-3382 (2019) Article DOI: 10.1016/j.bmc.2019.06.020 BindingDB Entry DOI: 10.7270/Q2988BDQ
Shanghai Jiao Tong University Curated by ChEMBL					More data for this Ligand-Target Pair
Polypeptide N-acetylgalactosaminyltransferase 2 (Homo sapiens (Human))	BDBM50215545 (CHEMBL6338) Show SMILES Oc1ccc2c3cc(O)c(O)cc3c(=O)oc2c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiao Tong University Curated by ChEMBL					Assay Description Inhibition of catalytic activity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293T cells and using 5-FAM labelled-EA2 peptide as subst...				Bioorg Med Chem 27: 3372-3382 (2019) Article DOI: 10.1016/j.bmc.2019.06.020 BindingDB Entry DOI: 10.7270/Q2988BDQ
Shanghai Jiao Tong University Curated by ChEMBL					More data for this Ligand-Target Pair
Polypeptide N-acetylgalactosaminyltransferase 2 (Homo sapiens (Human))	BDBM50215545 (CHEMBL6338) Show SMILES Oc1ccc2c3cc(O)c(O)cc3c(=O)oc2c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiao Tong University Curated by ChEMBL					Assay Description Inhibition of catalytic activity of human recombinant FLAG-tagged ppGalNAcT2 using Muc2 peptide as substrate incubated for 30 mins by HPLC-based enzy...				Bioorg Med Chem 27: 3372-3382 (2019) Article DOI: 10.1016/j.bmc.2019.06.020 BindingDB Entry DOI: 10.7270/Q2988BDQ
Shanghai Jiao Tong University Curated by ChEMBL					More data for this Ligand-Target Pair
Polypeptide N-acetylgalactosaminyltransferase 2 (Homo sapiens (Human))	BDBM50215545 (CHEMBL6338) Show SMILES Oc1ccc2c3cc(O)c(O)cc3c(=O)oc2c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiao Tong University Curated by ChEMBL					Assay Description Inhibition of catalytic activity of human recombinant FLAG-tagged ppGalNAcT2 using Muc7 peptide as substrate incubated for 30 mins by HPLC-based enzy...				Bioorg Med Chem 27: 3372-3382 (2019) Article DOI: 10.1016/j.bmc.2019.06.020 BindingDB Entry DOI: 10.7270/Q2988BDQ
Shanghai Jiao Tong University Curated by ChEMBL					More data for this Ligand-Target Pair
Polypeptide N-acetylgalactosaminyltransferase 2 (Homo sapiens (Human))	BDBM50215545 (CHEMBL6338) Show SMILES Oc1ccc2c3cc(O)c(O)cc3c(=O)oc2c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiao Tong University Curated by ChEMBL					Assay Description Inhibition of catalytic activity of human recombinant FLAG-tagged ppGalNAcT2 using Muc5AC peptide as substrate incubated for 30 mins by HPLC-based en...				Bioorg Med Chem 27: 3372-3382 (2019) Article DOI: 10.1016/j.bmc.2019.06.020 BindingDB Entry DOI: 10.7270/Q2988BDQ
Shanghai Jiao Tong University Curated by ChEMBL					More data for this Ligand-Target Pair
Polypeptide N-acetylgalactosaminyltransferase 2 (Homo sapiens (Human))	BDBM50215545 (CHEMBL6338) Show SMILES Oc1ccc2c3cc(O)c(O)cc3c(=O)oc2c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiao Tong University Curated by ChEMBL					Assay Description Inhibition of catalytic activity of human recombinant FLAG-tagged ppGalNAcT2 W282A mutant expressed in HEK293 cells using EA2 peptide as substrate by...				Bioorg Med Chem 27: 3372-3382 (2019) Article DOI: 10.1016/j.bmc.2019.06.020 BindingDB Entry DOI: 10.7270/Q2988BDQ
Shanghai Jiao Tong University Curated by ChEMBL					More data for this Ligand-Target Pair
Polypeptide N-acetylgalactosaminyltransferase 2 (Homo sapiens (Human))	BDBM50215545 (CHEMBL6338) Show SMILES Oc1ccc2c3cc(O)c(O)cc3c(=O)oc2c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	294	n/a	n/a	n/a	n/a	n/a
Shanghai Jiao Tong University Curated by ChEMBL					Assay Description Binding affinity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells assessed as dissociation constant by SPR analysis				Bioorg Med Chem 27: 3372-3382 (2019) Article DOI: 10.1016/j.bmc.2019.06.020 BindingDB Entry DOI: 10.7270/Q2988BDQ
Shanghai Jiao Tong University Curated by ChEMBL					More data for this Ligand-Target Pair
Polypeptide N-acetylgalactosaminyltransferase 2 (Homo sapiens (Human))	BDBM50215545 (CHEMBL6338) Show SMILES Oc1ccc2c3cc(O)c(O)cc3c(=O)oc2c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	3.53E+3	n/a	n/a
Shanghai Jiao Tong University Curated by ChEMBL					Assay Description Binding affinity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells assessed as association rate by SPR analysis				Bioorg Med Chem 27: 3372-3382 (2019) Article DOI: 10.1016/j.bmc.2019.06.020 BindingDB Entry DOI: 10.7270/Q2988BDQ
Shanghai Jiao Tong University Curated by ChEMBL					More data for this Ligand-Target Pair
Polypeptide N-acetylgalactosaminyltransferase 2 (Homo sapiens (Human))	BDBM50215545 (CHEMBL6338) Show SMILES Oc1ccc2c3cc(O)c(O)cc3c(=O)oc2c1O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	0.00104	n/a	n/a	n/a
Shanghai Jiao Tong University Curated by ChEMBL					Assay Description Binding affinity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells assessed as dissociation rate by SPR analysis				Bioorg Med Chem 27: 3372-3382 (2019) Article DOI: 10.1016/j.bmc.2019.06.020 BindingDB Entry DOI: 10.7270/Q2988BDQ
Shanghai Jiao Tong University Curated by ChEMBL					More data for this Ligand-Target Pair