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Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyphenol oxidase 2' and Ligand = 'BDBM50344058'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Polyphenol oxidase 2


(Agaricus bisporus (Common mushroom))
BDBM50344058
PNG
(6-Bromo-8-methoxy-3-(4'-methoxyphenyl)coumarin | C...)
Show SMILES COc1ccc(cc1)-c1cc2cc(Br)cc(OC)c2oc1=O
Show InChI InChI=1S/C17H13BrO4/c1-20-13-5-3-10(4-6-13)14-8-11-7-12(18)9-15(21-2)16(11)22-17(14)19/h3-9H,1-2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.36E+6n/an/an/an/an/an/a



Universidad de Santiago de Compostela

Curated by ChEMBL


Assay Description
Inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate measured for 5 mins by spectrophotometric analysis


Bioorg Med Chem Lett 21: 3342-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.012
BindingDB Entry DOI: 10.7270/Q2QF8T68
More data for this
Ligand-Target Pair