Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM179810'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM179810 (Myxochelin J5) Show SMILES OC[C@H](CCCCNC(=O)c1ccccc1O)NC(=O)c1ccccc1O |r| Show InChI InChI=1S/C20H24N2O5/c23-13-14(22-20(27)16-9-2-4-11-18(16)25)7-5-6-12-21-19(26)15-8-1-3-10-17(15)24/h1-4,8-11,14,23-25H,5-7,12-13H2,(H,21,26)(H,22,27)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hans Knöll Institute					Assay Description Purified 5-LO was diluted in PBS containing EDTA (1 mM) and freshly added ATP (1 mM) and incubated with the myxochelin test substances for 10 min at ...				Chembiochem 16: 2445-50 (2015) Article DOI: 10.1002/cbic.201500446 BindingDB Entry DOI: 10.7270/Q2R2105R
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