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Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50000534'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyunsaturated fatty acid 5-lipoxygenase


(Rattus norvegicus)		BDBM50000534
PNG
(2-Phenethyl-6-[3-(pyridin-4-ylsulfanyl)-propyl]-2,...)
Show SMILES Oc1cc2CC(CCc3ccccc3)Oc2cc1CCCSc1ccncc1
Show InChI InChI=1S/C24H25NO2S/c26-23-16-20-15-21(9-8-18-5-2-1-3-6-18)27-24(20)17-19(23)7-4-14-28-22-10-12-25-13-11-22/h1-3,5-6,10-13,16-17,21,26H,4,7-9,14-15H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 8n/an/an/an/an/an/a



Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL


Assay Description
Tested for its inhibitory activity against arachidonic acid in rat 5-lipoxygenase.

J Med Chem 35: 1299-318 (1992)


BindingDB Entry DOI: 10.7270/Q25X27WS
More data for this
Ligand-Target Pair