Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50000855'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50000855 (6-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl...) Show SMILES COC1(CCOCC1)c1cc(F)cc(OCc2ccc3[nH]c(=O)ccc3c2)c1 Show InChI InChI=1S/C22H22FNO4/c1-26-22(6-8-27-9-7-22)17-11-18(23)13-19(12-17)28-14-15-2-4-20-16(10-15)3-5-21(25)24-20/h2-5,10-13H,6-9,14H2,1H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of leukotriene B4 synthesis in human whole blood by inhibiting 5-lipoxygenase				J Med Chem 35: 2600-9 (1992) BindingDB Entry DOI: 10.7270/Q2Q240VJ
					More data for this Ligand-Target Pair