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Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50003463'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyunsaturated fatty acid 5-lipoxygenase


(Rattus norvegicus)		BDBM50003463
PNG
(2-(4-Fluoro-phenyl)-3-(hydroxy-methyl-amino)-1-(4-...)
Show SMILES CSc1ccc(cc1)C(=O)C(=C/N(C)O)\c1ccc(F)cc1
Show InChI InChI=1S/C17H16FNO2S/c1-19(21)11-16(12-3-7-14(18)8-4-12)17(20)13-5-9-15(22-2)10-6-13/h3-11,21H,1-2H3/b16-11-
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a>2.50E+4n/an/an/an/an/an/a



Du Pont Merck Pharmaceutical Company

Curated by ChEMBL


Assay Description
inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cell line.

J Med Chem 35: 4061-8 (1992)


BindingDB Entry DOI: 10.7270/Q2BC3XHJ
More data for this
Ligand-Target Pair