BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50003464'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyunsaturated fatty acid 5-lipoxygenase


(Rattus norvegicus)		BDBM50003464
PNG
(3-(Benzyl-hydroxy-amino)-1-(4-nitro-phenyl)-propen...)
Show SMILES [O-][N+](=O)c1ccc(cc1)C(=O)[CH-]C[N+](=O)Cc1ccccc1
Show InChI InChI=1S/C16H14N2O4/c19-16(14-6-8-15(9-7-14)18(21)22)10-11-17(20)12-13-4-2-1-3-5-13/h1-10H,11-12H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



Du Pont Merck Pharmaceutical Company

Curated by ChEMBL


Assay Description
inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cell line.

J Med Chem 35: 4061-8 (1992)


BindingDB Entry DOI: 10.7270/Q2BC3XHJ
More data for this
Ligand-Target Pair