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Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50006810'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))		BDBM50006810
PNG
(4-[4-(2,5-Dimethyl-pyrrol-1-yl)-phenyl]-but-3-enoi...)
Show SMILES CN(O)C(=O)C\C=C\c1ccc(cc1)-n1c(C)ccc1C
Show InChI InChI=1S/C17H20N2O2/c1-13-7-8-14(2)19(13)16-11-9-15(10-12-16)5-4-6-17(20)18(3)21/h4-5,7-12,21H,6H2,1-3H3/b5-4+
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Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
The compound was tested for inhibitory activity against 5-Lipoxygenase in guinea pig polymorphonuclear leukocytes

J Med Chem 35: 2501-24 (1992)


BindingDB Entry DOI: 10.7270/Q23B60R4
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Ligand-Target Pair