Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50022555'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022555 (4-Hydroxy-2,8-bis-trifluoromethyl-quinoline-3-carb...) Show SMILES Oc1c(C(=O)Nc2nccs2)c(nc2c(cccc12)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C15H7F6N3O2S/c16-14(17,18)7-3-1-2-6-9(7)23-11(15(19,20)21)8(10(6)25)12(26)24-13-22-4-5-27-13/h1-5H,(H,23,25)(H,22,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Roussel Uclaf Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase from rat peritoneal neutrophils after oral administration				J Med Chem 31: 1453-62 (1988) BindingDB Entry DOI: 10.7270/Q2JM2B7T
					More data for this Ligand-Target Pair