Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50048007'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50048007 (5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-3...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2-c2nnc(S)o2)c1Cl Show InChI InChI=1S/C15H11Cl2N3OS/c1-8-6-7-10(16)13(12(8)17)18-11-5-3-2-4-9(11)14-19-20-15(22)21-14/h2-7,18H,1H3,(H,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against 5-lipoxygenase was determined				Bioorg Med Chem Lett 2: 69-72 (1992) Article DOI: 10.1016/S0960-894X(00)80657-5 BindingDB Entry DOI: 10.7270/Q29K4B4Q
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50048007 (5-[2-(2,6-Dichloro-3-methyl-phenylamino)-phenyl]-3...) Show SMILES Cc1ccc(Cl)c(Nc2ccccc2-c2nnc(S)o2)c1Cl Show InChI InChI=1S/C15H11Cl2N3OS/c1-8-6-7-10(16)13(12(8)17)18-11-5-3-2-4-9(11)14-19-20-15(22)21-14/h2-7,18H,1H3,(H,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition 5-lipoxygenase mediated LTB4 formation in rat basophilic leukemia (RBL-1) cells				J Med Chem 36: 1802-10 (1993) BindingDB Entry DOI: 10.7270/Q2542MPQ
					More data for this Ligand-Target Pair