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Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50085226'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Polyunsaturated fatty acid 5-lipoxygenase


(Homo sapiens (Human))		BDBM50085226
PNG
(CHEMBL348398 | {[2-Chloro-4-(5-fluoro-benzothiazol...)
Show SMILES OC(=O)\C=N\OC(C1CCCCC1)c1ccc(OCc2nc3cc(F)ccc3s2)cc1Cl
Show InChI InChI=1S/C23H22ClFN2O4S/c24-18-11-16(30-13-21-27-19-10-15(25)6-9-20(19)32-21)7-8-17(18)23(31-26-12-22(28)29)14-4-2-1-3-5-14/h6-12,14,23H,1-5,13H2,(H,28,29)/b26-12+
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n/an/a 14n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of calcium ionophore (A-23187)-stimulated LTB4 formation in human neutrophil assay

J Med Chem 43: 690-705 (2000)


BindingDB Entry DOI: 10.7270/Q2HD7WCR
More data for this
Ligand-Target Pair