Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50231992'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50231992 (CHEMBL4067007) Show SMILES COC1=CC(=O)C(OC)=C(C(O)CCCCCCCCCO)C1=O |t:2,8| Show InChI InChI=1S/C18H28O6/c1-23-15-12-14(21)18(24-2)16(17(15)22)13(20)10-8-6-4-3-5-7-9-11-19/h12-13,19-20H,3-11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Second University of Naples Curated by ChEMBL					Assay Description Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of A23187-induced product formation using arachidonic acid as substrate prei...				Eur J Med Chem 127: 715-726 (2017) Article DOI: 10.1016/j.ejmech.2016.10.046 BindingDB Entry DOI: 10.7270/Q2DR2XQ8
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50231992 (CHEMBL4067007) Show SMILES COC1=CC(=O)C(OC)=C(C(O)CCCCCCCCCO)C1=O |t:2,8| Show InChI InChI=1S/C18H28O6/c1-23-15-12-14(21)18(24-2)16(17(15)22)13(20)10-8-6-4-3-5-7-9-11-19/h12-13,19-20H,3-11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Second University of Naples Curated by ChEMBL					Assay Description Inhibition of recombinant human 5-lipoxygenase expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 15 mins follow...				Eur J Med Chem 127: 715-726 (2017) Article DOI: 10.1016/j.ejmech.2016.10.046 BindingDB Entry DOI: 10.7270/Q2DR2XQ8
					More data for this Ligand-Target Pair