Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM91669'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM91669 (N-aryl-4-aryl-1,3-thiazole-2-amine, 25) Show SMILES Nc1ccc(Nc2nc(cs2)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C15H12FN3S/c16-11-3-1-10(2-4-11)14-9-20-15(19-14)18-13-7-5-12(17)6-8-13/h1-9H,17H2,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	7.4	25
Korea Research Institute of Chemical Technology					Assay Description 5-LOX enzyme assay was carried out with some modifications of ferric oxidation of xylenol orange (FOX) assay, which is based on the complex formation...				Chem Biol Drug Des 80: 89-98 (2012) Article DOI: 10.1111/j.1747-0285.2012.01371.x BindingDB Entry DOI: 10.7270/Q21G0JW1
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