BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid lipoxygenase ALOX12' and Ligand = 'BDBM50025735'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Polyunsaturated fatty acid lipoxygenase ALOX12 (Homo sapiens (Human))	BDBM50025735 ((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Mixed type inhibition of human platelet 12-lipoxygenase assessed as equilibrium inhibitor constant of dissociation from enzyme by measuring 12-HpETE ...				Bioorg Med Chem 22: 4293-7 (2014) Article DOI: 10.1016/j.bmc.2014.05.025 BindingDB Entry DOI: 10.7270/Q2NP2613
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Polyunsaturated fatty acid lipoxygenase ALOX12 (Homo sapiens (Human))	BDBM50025735 ((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human platelet 12-lipoxygenase by UV-visible spectrophotometry				Bioorg Med Chem 22: 4293-7 (2014) Article DOI: 10.1016/j.bmc.2014.05.025 BindingDB Entry DOI: 10.7270/Q2NP2613
University of California Curated by ChEMBL					More data for this Ligand-Target Pair