Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polyunsaturated fatty acid lipoxygenase ALOX15 (Homo sapiens (Human)) | BDBM49390 ((6Z)-3-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysis | Bioorg Med Chem 24: 1183-90 (2016) Article DOI: 10.1016/j.bmc.2016.01.042 BindingDB Entry DOI: 10.7270/Q2QJ7K44 | |||||||||||
More data for this Ligand-Target Pair |