Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium channel subfamily K member 18 (Homo sapiens (Human)) | BDBM17636 (2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Activation of human TRESK channel relative to control | Bioorg Med Chem Lett 26: 4919-4924 (2016) Article DOI: 10.1016/j.bmcl.2016.09.020 BindingDB Entry DOI: 10.7270/Q2T72KDN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium channel subfamily K member 18 (Homo sapiens (Human)) | BDBM17636 (2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.74E+5 | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Activation of human TRESK channel expressed in HEK293 cells assessed as induction of channel current by whole cell patch clamp assay | Bioorg Med Chem Lett 26: 4919-4924 (2016) Article DOI: 10.1016/j.bmcl.2016.09.020 BindingDB Entry DOI: 10.7270/Q2T72KDN | |||||||||||
More data for this Ligand-Target Pair |