Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Potassium channel subfamily K member 3' and Ligand = 'BDBM179663'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM179663 (US9127001, 6aq | US9598410, Compound 6aq) Show SMILES CC(=O)N1CCc2c(C1)c(nn2Cc1c(F)cccc1F)-c1ccc(F)cc1 Show InChI InChI=1S/C21H18F3N3O/c1-13(28)26-10-9-20-17(11-26)21(14-5-7-15(22)8-6-14)25-27(20)12-16-18(23)3-2-4-19(16)24/h2-8H,9-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	359	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliated. Subsequently, TA...				US Patent US9598410 (2017) BindingDB Entry DOI: 10.7270/Q2377BRM
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 3 (Homo sapiens (Human))	BDBM179663 (US9127001, 6aq | US9598410, Compound 6aq) Show SMILES CC(=O)N1CCc2c(C1)c(nn2Cc1c(F)cccc1F)-c1ccc(F)cc1 Show InChI InChI=1S/C21H18F3N3O/c1-13(28)26-10-9-20-17(11-26)21(14-5-7-15(22)8-6-14)25-27(20)12-16-18(23)3-2-4-19(16)24/h2-8H,9-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	359	n/a	n/a	n/a	n/a	n/a	25
Sanofi US Patent					Assay Description Human TASK-1 channels were expressed in Xenopus oocytes. For this purpose, oocytes were isolated from Xenopus laevis and defoliculated. Subsequently,...				US Patent US9127001 (2015) BindingDB Entry DOI: 10.7270/Q2HM576Z
					More data for this Ligand-Target Pair