Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM242749 (US10030025, Compound 13 | US10836768, Cpd no 13 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
EUROSCREEN SA US Patent | Assay Description The hERG inhibition study aims at quantifying the in vitro effects of compounds of the invention on the potassium-selective IKr current generated in ... | US Patent US9422299 (2016) BindingDB Entry DOI: 10.7270/Q2GM866C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM242749 (US10030025, Compound 13 | US10836768, Cpd no 13 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ogeda SA US Patent | Assay Description The human ether-a-go-go related gene (hERG) encodes the inward rectifying voltage gated potassium channel in the heart (Igr) which is involved in car... | US Patent US10836768 (2020) BindingDB Entry DOI: 10.7270/Q2Z03C74 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM242749 (US10030025, Compound 13 | US10836768, Cpd no 13 | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
OGEDA SA US Patent | Assay Description The human ether-a-go-go related gene (hERG) encodes the inward rectifying voltage gated potassium channel in the heart (IKr) which is involved in car... | US Patent US10030025 (2018) BindingDB Entry DOI: 10.7270/Q2B56MSG | |||||||||||
More data for this Ligand-Target Pair |