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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM388489'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM388489
PNG
(US9944618, Compound ID No. 23)
Show SMILES CNC[C@@H]([C@H](OCC(=O)N1CCOCC1)c1ccccc1)c1ccc2ccccc2c1 |r|
Show InChI InChI=1S/C26H30N2O3/c1-27-18-24(23-12-11-20-7-5-6-10-22(20)17-23)26(21-8-3-2-4-9-21)31-19-25(29)28-13-15-30-16-14-28/h2-12,17,24,26-27H,13-16,18-19H2,1H3/t24-,26-/m1/s1
PDB
MMDB

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n/an/a 2.10E+4n/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
HERG: The pre- and post-compound hERG current was evoked by a single voltage pulse consisting of a 20 s period holding at −70 mV, a 160 ms step...


Bioorg Med Chem Lett 19: 1164-7 (2009)


BindingDB Entry DOI: 10.7270/Q26D5WBR
More data for this
Ligand-Target Pair