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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50214365'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50214365
PNG
(24-{[(2-{[2-(4-methanesulfonamidophenoxy)ethyl][2-...)
Show SMILES CC1(C)C2=C3C=C4C(CC[N+]5=C4C(C)(C)c4cc(ccc54)S([O-])(=O)=O)OC3CCN2c2ccc(CC(=O)NCCN(CCOc3ccc(NS(C)(=O)=O)cc3)CCc3ccc(NS(C)(=O)=O)cc3)cc12 |w:26.28,7.27,c:3,5,10|
Show InChI InChI=1S/C51H60N6O10S3/c1-50(2)41-29-34(30-47(58)52-22-26-55(23-19-33-7-10-35(11-8-33)53-68(5,59)60)27-28-66-37-14-12-36(13-15-37)54-69(6,61)62)9-17-43(41)56-24-20-45-39(48(50)56)32-40-46(67-45)21-25-57-44-18-16-38(70(63,64)65)31-42(44)51(3,4)49(40)57/h7-18,29,31-32,45-46,53-54H,19-28,30H2,1-6H3,(H-,52,58,63,64,65)
PDB
MMDB

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PC cid
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Article
PubMed
7.30E+3n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]dofetilide from hERG expressed in HEK293 cells by SPA


J Med Chem 50: 2931-41 (2007)


Article DOI: 10.1021/jm0700565
BindingDB Entry DOI: 10.7270/Q2736RR2
More data for this
Ligand-Target Pair