Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50247739'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50247739 (CHEMBL4074324) Show SMILES CCOC(=O)C1=C(CN2CC(C)(C)OC[C@H]2C(O)=O)NC(=N[C@H]1c1ccc(F)cc1Br)c1nccs1 |r,c:5,21| Show InChI InChI=1S/C24H26BrFN4O5S/c1-4-34-23(33)18-16(10-30-12-24(2,3)35-11-17(30)22(31)32)28-20(21-27-7-8-36-21)29-19(18)14-6-5-13(26)9-15(14)25/h5-9,17,19H,4,10-12H2,1-3H3,(H,28,29)(H,31,32)/t17-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
HEC Pharma Group Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in HEK293 cells at -80 mV holding potential by manual-patch-clamp electrophysiology assay				J Med Chem 61: 1355-1374 (2018) Article DOI: 10.1021/acs.jmedchem.7b01914 BindingDB Entry DOI: 10.7270/Q2XS5XS9
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