Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50262770'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50262770 (CHEMBL4101684) Show SMILES NC(=O)c1c(NC(=O)Nc2ccc(Cl)cc2)sc2CN(CCCNC(=O)CCc3c[nH]c4ccccc34)CCc12 Show InChI InChI=1S/C29H31ClN6O3S/c30-19-7-9-20(10-8-19)34-29(39)35-28-26(27(31)38)22-12-15-36(17-24(22)40-28)14-3-13-32-25(37)11-6-18-16-33-23-5-2-1-4-21(18)23/h1-2,4-5,7-10,16,33H,3,6,11-15,17H2,(H2,31,38)(H,32,37)(H2,34,35,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Merrill Bloedel Hearing Research Center, University of Washington , Seattle, Washington 98195, United States. Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in HEK293 cells assessed as decrease in peak tail current amplitude by path clamp method				J Med Chem 61: 84-97 (2018) Article DOI: 10.1021/acs.jmedchem.7b00932 BindingDB Entry DOI: 10.7270/Q2697615
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