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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily H member 2' and Ligand = 'BDBM50402396'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Potassium voltage-gated channel subfamily H member 2


(Homo sapiens (Human))
BDBM50402396
PNG
(CHEMBL2207737)
Show SMILES NC(=O)C1CCN(CCOc2ccc(Oc3nc4ncccc4s3)cc2)CC1
Show InChI InChI=1S/C20H22N4O3S/c21-18(25)14-7-10-24(11-8-14)12-13-26-15-3-5-16(6-4-15)27-20-23-19-17(28-20)2-1-9-22-19/h1-6,9,14H,7-8,10-13H2,(H2,21,25)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Janssen Research& Development LLC

Curated by ChEMBL


Assay Description
Inhibition of dofetilide binding to human ERG by patch clamp assay


Bioorg Med Chem Lett 22: 7504-11 (2012)


Article DOI: 10.1016/j.bmcl.2012.10.036
BindingDB Entry DOI: 10.7270/Q2ZG6TDQ
More data for this
Ligand-Target Pair