Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily KQT member 2' and Ligand = 'BDBM50395463'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily KQT member 2 (Homo sapiens (Human))	BDBM50395463 (CHEMBL2163682) Show SMILES CCC(C(=O)Nc1ccccc1-n1c(C)ccc1C)c1ccccc1 |(14.86,-21.63,;13.53,-22.39,;12.2,-21.61,;10.86,-22.36,;10.84,-23.89,;9.53,-21.58,;8.19,-22.33,;8.17,-23.87,;6.83,-24.62,;5.5,-23.84,;5.52,-22.3,;6.87,-21.54,;6.88,-20,;5.65,-19.09,;4.19,-19.54,;6.14,-17.63,;7.68,-17.65,;8.14,-19.12,;9.6,-19.61,;12.22,-20.07,;10.89,-19.28,;10.91,-17.74,;12.25,-16.99,;13.57,-17.77,;13.56,-19.31,)| Show InChI InChI=1S/C22H24N2O/c1-4-19(18-10-6-5-7-11-18)22(25)23-20-12-8-9-13-21(20)24-16(2)14-15-17(24)3/h5-15,19H,4H2,1-3H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Agonist activity at KCNQ2 expressed in CHO cells incubated for 3 mins by automated patch clamp assay				J Med Chem 55: 6975-9 (2012) Article DOI: 10.1021/jm300700v BindingDB Entry DOI: 10.7270/Q2KD2017
					More data for this Ligand-Target Pair