Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM193028'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM193028 (US9193726, 16) Show SMILES Cc1cn(cn1)-c1ccc2C(=O)N(C[C@H]3CCC[C@H](O3)c3ccc(cc3)C(F)(F)F)CCn2c1=O Show InChI InChI=1S/C25H25F3N4O3/c1-16-13-31(15-29-16)20-9-10-21-23(33)30(11-12-32(21)24(20)34)14-19-3-2-4-22(35-19)17-5-7-18(8-6-17)25(26,27)28/h5-10,13,15,19,22H,2-4,11-12,14H2,1H3/t19-,22+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	96.6	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description The ability of compounds to modulate production of amyloid beta protein Abeta(1-42) was determined using human WT-APP overexpressing CHO cells. Cel...				US Patent US9193726 (2015) BindingDB Entry DOI: 10.7270/Q22B8WT7
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