Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM193036'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM193036 (US9193726, 24) Show SMILES Cc1cn(cn1)-c1ccc2C(=O)N(CCn2c1=O)[C@@H]1CCC[C@@H]1c1cc(F)cc(F)c1 Show InChI InChI=1S/C23H22F2N4O2/c1-14-12-27(13-26-14)20-5-6-21-23(31)28(7-8-29(21)22(20)30)19-4-2-3-18(19)15-9-16(24)11-17(25)10-15/h5-6,9-13,18-19H,2-4,7-8H2,1H3/t18-,19-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	563	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description The ability of compounds to modulate production of amyloid beta protein Abeta(1-42) was determined using human WT-APP overexpressing CHO cells. Cel...				US Patent US9193726 (2015) BindingDB Entry DOI: 10.7270/Q22B8WT7
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