Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM193044'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM193044 (US9193726, 32) Show SMILES Cc1cn(cn1)-c1ccc2C(=O)N(CC3CC(=NO3)c3cccc(c3Cl)C(F)(F)F)CCn2c1=O |c:17| Show InChI InChI=1S/C23H19ClF3N5O3/c1-13-10-31(12-28-13)18-5-6-19-21(33)30(7-8-32(19)22(18)34)11-14-9-17(29-35-14)15-3-2-4-16(20(15)24)23(25,26)27/h2-6,10,12,14H,7-9,11H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	429	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description The ability of compounds to modulate production of amyloid beta protein Abeta(1-42) was determined using human WT-APP overexpressing CHO cells. Cel...				US Patent US9193726 (2015) BindingDB Entry DOI: 10.7270/Q22B8WT7
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