Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM193071'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM193071 (US9193726, 59) Show SMILES Cc1cn(cn1)-c1ccc2C(=O)N(C[C@H]3CC[C@H](O3)c3ccc(cc3)C(F)(F)C(F)(F)F)CCn2c1=O Show InChI InChI=1S/C25H23F5N4O3/c1-15-12-33(14-31-15)19-7-8-20-22(35)32(10-11-34(20)23(19)36)13-18-6-9-21(37-18)16-2-4-17(5-3-16)24(26,27)25(28,29)30/h2-5,7-8,12,14,18,21H,6,9-11,13H2,1H3/t18-,21+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description The ability of compounds to modulate production of amyloid beta protein Abeta(1-42) was determined using human WT-APP overexpressing CHO cells. Cel...				US Patent US9193726 (2015) BindingDB Entry DOI: 10.7270/Q22B8WT7
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