Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50150511'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM50150511 (CHEMBL3770902) Show SMILES Cc1cn(cn1)-c1ccc2c(CCc3ccc(Cc4ccc(F)cc4)nc3C2=O)c1 Show InChI InChI=1S/C25H20FN3O/c1-16-14-29(15-27-16)22-10-11-23-19(13-22)5-4-18-6-9-21(28-24(18)25(23)30)12-17-2-7-20(26)8-3-17/h2-3,6-11,13-15H,4-5,12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Modulation of gamma secretase in human H4 cells assessed as inhibition of amyloid beta (1 to 42) production				Bioorg Med Chem Lett 26: 1498-502 (2016) Article DOI: 10.1016/j.bmcl.2015.06.020 BindingDB Entry DOI: 10.7270/Q2CZ3910
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