Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Presenilin-1 (Homo sapiens (Human)) | BDBM50477329 (CHEMBL392028) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Darmstadt University of Technology Curated by ChEMBL | Assay Description Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta-42 formation LPECL assay | Bioorg Med Chem Lett 17: 5428-31 (2007) Article DOI: 10.1016/j.bmcl.2007.07.044 BindingDB Entry DOI: 10.7270/Q28P63B0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477329 (CHEMBL392028) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Darmstadt University of Technology Curated by ChEMBL | Assay Description Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta42 formation LPECL assay | Bioorg Med Chem Lett 17: 176-82 (2007) Article DOI: 10.1016/j.bmcl.2006.09.061 BindingDB Entry DOI: 10.7270/Q2GB26TD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477329 (CHEMBL392028) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Darmstadt University of Technology Curated by ChEMBL | Assay Description Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta-38 formation by LPECL assay | Bioorg Med Chem Lett 17: 176-82 (2007) Article DOI: 10.1016/j.bmcl.2006.09.061 BindingDB Entry DOI: 10.7270/Q2GB26TD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477329 (CHEMBL392028) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Darmstadt University of Technology Curated by ChEMBL | Assay Description Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta-40 formation LPECL assay | Bioorg Med Chem Lett 17: 176-82 (2007) Article DOI: 10.1016/j.bmcl.2006.09.061 BindingDB Entry DOI: 10.7270/Q2GB26TD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477329 (CHEMBL392028) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Darmstadt University of Technology Curated by ChEMBL | Assay Description Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as reduction of Amyloid beta-40 formation LPECL assay | Bioorg Med Chem Lett 17: 5428-31 (2007) Article DOI: 10.1016/j.bmcl.2007.07.044 BindingDB Entry DOI: 10.7270/Q28P63B0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Presenilin-1 (Homo sapiens (Human)) | BDBM50477329 (CHEMBL392028) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a |
Darmstadt University of Technology Curated by ChEMBL | Assay Description Effect on gamma-secretase activity in human H4 cells expressing APP695 assessed as increase in Amyloid beta38 formation by LPECL assay | Bioorg Med Chem Lett 17: 5428-31 (2007) Article DOI: 10.1016/j.bmcl.2007.07.044 BindingDB Entry DOI: 10.7270/Q28P63B0 | |||||||||||
More data for this Ligand-Target Pair |