Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50483261'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM50483261 (CHEMBL1643436) Show SMILES COc1cc(ccc1-n1cnc(C)c1)-c1nnc2N(CCCn12)C(=O)N1CCOCC1 Show InChI InChI=1S/C21H25N7O3/c1-15-13-26(14-22-15)17-5-4-16(12-18(17)30-2)19-23-24-20-27(19)6-3-7-28(20)21(29)25-8-10-31-11-9-25/h4-5,12-14H,3,6-11H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of gamma secretase-mediated amyloid beta42 production in HEK293 cells by sandwich immunoassay				Bioorg Med Chem Lett 21: 664-9 (2011) Article DOI: 10.1016/j.bmcl.2010.12.012 BindingDB Entry DOI: 10.7270/Q2930X12
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