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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50485692'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Presenilin-1


(Homo sapiens (Human))		BDBM50485692
PNG
(CHEMBL2152870)
Show SMILES [H][C@]12O[C@]([H])(C[C@@H](C)[C@]1([H])[C@@]1(C)CC[C@@]34C[C@@]33CC[C@H](O[C@@]5([H])CNCCO5)C(C)(C)[C@]3([H])CC[C@@]4([H])[C@]1(C)[C@H]2O)[C@H](OC(C)=O)C(C)(C)O |r|
Show InChI InChI=1S/C36H59NO7/c1-20-17-22(30(32(5,6)40)42-21(2)38)43-28-27(20)33(7)13-14-36-19-35(36)12-11-25(44-26-18-37-15-16-41-26)31(3,4)23(35)9-10-24(36)34(33,8)29(28)39/h20,22-30,37,39-40H,9-19H2,1-8H3/t20-,22-,23+,24+,25+,26+,27+,28+,29+,30+,33-,34-,35-,36+/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>4.00E+3n/an/an/an/an/an/a



Satori Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of gamma-secretase-mediated notch processing in human SUP-T1 cells after 1 hr by luminescent assay

ACS Med Chem Lett 3: 908-13 (2012)


Article DOI: 10.1021/ml300256p
BindingDB Entry DOI: 10.7270/Q29G5QPS
More data for this
Ligand-Target Pair