Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Presenilin-1' and Ligand = 'BDBM50533487'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Homo sapiens (Human))	BDBM50533487 (CHEMBL4583737) Show SMILES Cc1cn(cn1)-c1ccc(cc1F)-c1csc(Nc2c3CCCCc3nn2C2CCOCC2)n1 Show InChI InChI=1S/C25H27FN6OS/c1-16-13-31(15-27-16)23-7-6-17(12-20(23)26)22-14-34-25(28-22)29-24-19-4-2-3-5-21(19)30-32(24)18-8-10-33-11-9-18/h6-7,12-15,18H,2-5,8-11H2,1H3,(H,28,29)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	766	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Modulation of gamma-secretase in human SH-SY5Y cells overexpressing wild-type human APP751 assessed as inhibition of Abeta42 level after 24 hrs by EL...				Bioorg Med Chem Lett 26: 3928-37 (2016) Article DOI: 10.1016/j.bmcl.2016.07.011 BindingDB Entry DOI: 10.7270/Q2K077SR
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