Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Presenilin-1 (Homo sapiens (Human)) | BDBM50534369 (E-2212 | E2212) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a |
FORUM Pharmaceuticals Curated by ChEMBL | Assay Description Modulation of human gamma-secretase assessed as inhibition of amyloid beta (1 to 42 residues) production by ELISA | J Med Chem 59: 7389-409 (2016) Article DOI: 10.1021/acs.jmedchem.5b01960 BindingDB Entry DOI: 10.7270/Q2B56P74 | |||||||||||
More data for this Ligand-Target Pair |